Straightforward and rapid modification techniques allow for the use of porous coordination cages in network solids, flexible adsorbents, and stimuli-responsive, peptide-based materials.
Porous coordination cages represent simple molecular versions of complex solid-state materials. While tunable, their modification remains challenging. This work details a new toolkit for the rapid modification of these cages.
- We have shown, for the first time, that click chemistry can be used to functionalize multiple families of porous cages.
- Incorporation of certain functional groups onto porous cages has been challenging, this approach can be used to dramatically expand the chemistry of porous cages.
- Utilization of porous cages as building blocks in peptide-based materials (IRG 1) was contingent on the development of modification techniques for the cages.
- With this toolkit in hand, work toward the development of higher-dimensional peptide bundlemers is progressing rapidly.
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Center for Hybrid, Active, and Responsive Materials (2020)
UD CHARM advances foundational understanding of new materials driven by theoretical and computational predictions paired with cutting-edge experiments to enable the integration of unconventional, ultra-small, building blocks.